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The CFTR KO mice utilized in this study possess the S489X truncation mutation resulting in a non functional CFTR

doi: 10.7196/SAMJ.2016.v106i8.10878

The formed lipid film was then hydrated with PBS (pH 7.4) and sonicated in a bath-type sonicator for 1 h at 50 C to get 5 mM final lipid dispersion

In this condition, the mutated receptors have a higher threshold for activation, requiring significantly elevated serum calcium concentrations to inhibit hormone release

Evaluation of the neuroprotective potential of N-acetylcysteine for prevention and treatment of cognitive aging and dementia

O'Brien S, Kantarjian H, Estey E, Koller C, Robertson LE, Beran M, Andreeff M , Pierce S, Keating M